By unlocking the vast potential of nature's molecular treasures, our research explores the synergies between engineered biosynthesis, enzymatic catalysis and organic synthesis, which together serve as powerful toolboxes for accessing and derivatizing natural products. We integrate metabolomics as an emerging and invaluable toolbox, enabling the identification of natural products and biosynthetic intermediates with unprecedented precision. This toolbox is also used to identify biomarkers in clinical settings and to identify bioactive compounds in probiotics.
We engineer the bioactivity of natural small molecules. This optimization could prove to be a turning point in our search for new antibiotics and anti-cancer activities. Our goal is to take traditional methods and marry them with up-to-date technology in an effort to extend the boundaries of what can be done in drug discovery.
Come with us on this journey where we combine a plethora of methods in order to find the unpublished resources natural compounds can offer. You will work in a dynamic environment with state-of-the-art infrastructure interested in the discovery and development of novel solutions for significant health problems, further establishing natural product-based drug discovery as a frontier field.
We are a team of chemists, biochemists, and biologists, united in the pursuit for novel medicinally active small molecules.
We investigate novel strategies and methods towards the identification and derivatization of compounds from natural sources.
Undergraduate research projects: We offer projects for talented and motivated undergraduate students in chemistry, biochemistry.
Lectures: We teach organic chemistry, natural product chemistry, enzyme biochemistry and genetics
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Phone: 0234-32-27034
Email: firstname.surname@rub.de
Fakultät für Chemie und Biochemie